Estudo clínico duplo cego randomizado avaliando o pós-operatório de terceiros molares inferiores inclusos após utilização de fibrina rica em plaquetas e leucócitos: estudo piloto

Abstract

The purpose of this study was to assess the effect of LPRF after mandibular third molar extraction. In this prospective, double bind, split-mouth study, 20 patients were evaluated. The patients were assessed for post-operative bone regeneration, pain and soft tissue healing. The evaluation of bone healing, primary outcome, was performed through tomographic evaluation in the immediate postoperative period and 3 months after the procedure. The ITK-SNAP software was used for image evaluation by the intensity of gray of each voxel. In the evaluation of secondary outcomes, the variables assessed were: pain, through visual and numerical analogue scale and soft tissue, using Landry et al. and pre and postoperative probing of the distal region of lower second molar. The evaluation of bone healing, primary outcome, showed a significant difference, with test group showing higher bone density after 3 months, p<0.05. The results found in the Test and Control Groups were then confronted searching differences between the two techniques. The values obtained through the visual and numerical analogue scale for pain evaluation were submitted to the t test, where p> 0.05. The parameters for evaluation of soft tissue and periodontal probing were submitted to the Mann-Whitney test, where p> 0.05. For the parameters pain and tissue healing there was no statistical difference between the groups.