Redução da morbimortalidade neonatal por asfixia perinatal com a hipotermia terapêutica induzida por sistema de resfriamento servocontrolado

Abstract

Therapeutic hypothermia is the currently recommended treatment for moderate to severe hypoxic-ischaemic encephalopathy in newborns, and since the introduction of the 2010 resuscitation guideline, when Hypothermia was recommended, the number of Centres to implement the threapy has grown.This study aims to estabilish a protocol for the clinical handling of these patients in the Neonatal Unit of the Pedro Ernesto University Hospital, utilizing a servocontrolled cooling system and the continuous neuromonitoring with amplitude-integrated EEG, and also, based on the estabilished protocol, transform the Unit into a Training Centre for health professionals. The proposed protocol for this study was based on the protocol used by the therapeutic hypothermia centres in various countries, and after one year of experience, numerous revisions and adaptations were made. As perinatal asphyxia is an important cause of neonatal morbidity and mortality, the training of professionals for the recognition and adequate clinical handling of these patients will contribute to a decrease in child mortality rates. The Neonatal Unit of the Pedro Ernesto University Hospital is a unit of assistence, teaching and research. It receives graduation and post-graduation students, besides health professionals, and thusly, contributes to the spread of knowledge.