Revisão sistemática sobre medidas de biossegurança em biotérios

Abstract

Biosecurity in vivariums is an essential aspect that involves rigorous planning and implementation of strategies to ensure worker safety, environmental protection and animal welfare. Biosafety measures refer to a set of practices and protocols adopted to minimize biological risks, protect human and animal health, and ensure environmental integrity. Although the biosafety measures in place comply with current legislation and standards, there are still gaps in the operational practices of biocenters, which makes the topic relevant for investigation. The objective of this systematic review was to critically analyze the impact of biosafety measures adopted in animal facilities, synthesizing the available scientific evidence and identifying opportunities for improvement in laboratory activities. The review was conducted following the PICO strategy, with the PRISMA recommendation and the ROBINS-I methodological quality assessment. The search was carried out in 5 databases on September 8, 2024. After applying the inclusion and exclusion criteria, only complete articles were included, excluding review and incomplete articles. The result of the review consisted of 10 included articles, which were analyzed using the methodological quality assessment tool. Most articles described the biosafety measures generally adopted during experiments. The conclusion reveals that, although biosafety measures in vivariums comply with several standards and guidelines, there are significant gaps in the practical application of these measures, especially with regard to monitoring effectiveness and needed, particularly in worker training and facility upgrades. These changes are essential to ensure the quality of experiments, animal welfare and environmental safety, in line with the One Health concept.