Influência da condição física sobre indicadores bioquímicos de lesão muscular e da capacidade antioxidante após treinamento militar intenso

Abstract

The regular physical activity is associated with several health benefits. However, if excessive, can lead to the occurrence of injuries and increased production of free radicals and reactive species. If this production exceeds antioxidant defenses, cell membranes can be damaged. However, the improvement in physical fitness can increase the antioxidant defenses and reduce the risk of muscle injury. The aim of this study was to investigate the influence of physical fitness on biochemical markers of muscle damage and antioxidant capacity in physically trained military. Total of 71 cadets took part in the study. Twelve days before performing three days of intense military training, an assessment of aerobic fitness (12 min test) and the lower limb muscle power was performed. Based on these tests, the cadets were classified as: Good (G), Excellent (E) and Superior (S). Before training (T1) and 24 hours later (T2), muscle damage was estimated by determination of serum LDH and CK MM, and the antioxidant capacity by the DPPH method. ANOVA 3 x 2 statistical analyze was performed. When stratified by aerobic power, there was a significant increase in CK and LDH, between T1 and T2, only in groups G (2105%, p = 0.03) and E (1469%, p <0.001). Also, at T2 the concentration of LDH was significantly higher in group G than in S (P = 0.004). In the DPPH analysis, stratifying by both aerobic power such as lower limb muscle power, the group S had a higher percentage of DPPH radical scavenging than the others (128.0%, p <0.0001; 121.5%, p <0 03, respectively). The results suggest that an increased concentration of muscle damage markers is less consistent in the groups with greater physical fitness and the increase in antioxidant capacity is more consistent in groups with greater fitness