Estudo e proposta de sistema para o processo de tipificação HLA praticado pelo Laboratório de HLA da UERJ

Abstract

Bioinformatics, by proposing the study of computer science techniques for application in the field of biology, has provided enormous advances in the molecular biology field. All this evolution has generated a large volume of biological data which needs increasingly use computer for analysis and storage of this information. In this context, the Histocompatibility and Cryopreservation Laboratory of Rio de Janeiro State University (HLA-UERJ), with the collaboration of the High Performance Computing Laboratory (LabCAD) also UERJ, has sought to use the technology in their activities with the aim to improve the quality of services provided. Thus, it is necessary to sistematize its workflows to allow a better understanding of the current processes. This study, using flowchart techniques, presents the mapping of the HLA typing activity praticed by HLA-UERJ and offers suggestions for improvement in the control and management of current procedures, presenting a workflow management system implementation proposal in a high availability architecture, with the main objectives to settle operational risks and increase the analysis capacity and traceability of the data generated