Efeito da associação do extrato aquoso de Chenopodium ambrosioides (mastruz) com vibrações mecânicas geradas em plataforma oscilante/vibratória na resposta de parâmetros fisiológicos em ratos Wistar

Abstract

Mechanical vibrations produced by oscillating/vibratory platform (OVP) can be transmitted to all body, when the individual is on the base of the platform turned on, generating whole body vibration (WBV) exercise. The effect of treatments involving substances (synthetic and natural products) associated with mechanical vibrations has been investigated. Chenopodium ambrosioides, known as mastruz, is an example of natural product used in the folk medicine as an anti-inflammatory, anthelmintic, antitumor and antimicrobial. Wistar rats (male/ n=20) were divided equally in four groups: control group (GC), treated with Chenopodium ambrosioides (GM), exposed to 50 Hz WBV (GP) and treated with Chenopodium ambrosioides and exposed to 50 Hz WBV (GPM) daily for 6-weeks. The body mass of the animals was determined weekly, the feed intake and the stool consistency was measured daily. After 6-weeks (forty days) of treatments, sample of blood was used for biochemical analysis. Along 6-weeks there is an increase (p<0.001) in the feed intake in VBR group and a decrease in the CHE group in comparison with other groups. The levels of aspartate aminotransferase (AST) in VBR+CHE group decreased (p<0.05) in comparison with other groups. No difference was found in body mass and stool consistency. In conclusion, the findings suggest that WBV can modify physiological parameters, such as increasing consumption without directly affecting body mass. In addition, EVCI in association with Chenopodium ambrosioides can alter the enzymatic activity of AST.