A relação entre a pressão arterial e o perfil antropométrico e metabólico de indivíduos jovens estratificados pelo comportamento da pressão arterial ao longo de 17 anos de acompanhamento: estudo do Rio de Janeiro

Abstract

Cardiovascular risk variables studies in young populations are important for primary prevention strategies. The objectives of the present study are the following: To evaluate BP, anthropometric and metabolic variables obtained during a 17 year-old period of follow-up in young subjects from the Rio de Janeiro Study. 115 subjects (64M) were submitted to three evaluations along 17 years (212,23±16,0months): E1 (12,97±1,48yo), E2(21,90±1,71yo) and E3 (30,65±2,00yo), and were divided in two groups: GN (n=84) normal BP in at least two evaluations; GH (n=31) abnormal BP in at least two evaluations. In the three occasions, BP and body mass index (BMI) were obtained. In E2 and E3, glucose, total cholesterol, LDL-c and HDL-c, triglycerides were added and in E3, abdominal circumference (AC) was also measured. The main results were: 1) Group H had higher BP, BMI and AC (p<0,001) and higher arterial hypertension (AH) and overweight/obesity (O/O) prevalences (p<0,003) in the three occasions; 2) Group H had higher LDL-c and glucose (p<0,05) in E2 and higher metabolic syndrome prevalence in E3 (p<0,0001); 4) Group H showed higher prevalence of the association AH+O/O and Group N had higher prevalence of the association normal BP + normal BMI (p<0,0001) in the three evaluations; 6) AH in E1 (OR:5,1956; p<0,0007), O/O in E1 (OR=3,3984; p<0,0278) and male gender (OR=5,2653; p<0,0019), were significantly associated to the occurrence of AH in young adulthood (E3). In conclusion, after a 17 year-old period of follow-up, BP obtained in childhood and adolescence was significantly related to cardiovascular risk variables and metabolic syndrome in young adulthood.